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Polynucleotides Under Eyes UK: Benefits, Results and What to Expect

05-05-2026 | Posted in: Blogs, Skin Treatments

The under-eye area is one of the most delicate parts of the face, often showing early signs of ageing such as fine lines, dark circles, and thinning skin. These changes can make the face appear tired, even when you feel well rested.

Polynucleotides under the eyes are a regenerative treatment designed to improve skin quality from within, offering a subtle and natural approach to under-eye rejuvenation.

“The under-eye area requires a careful approach. Polynucleotides are particularly effective because they improve the quality and strength of the skin, rather than simply adding volume.” – Dr Ioannis Liakas

What are polynucleotides?

Polynucleotides are DNA-derived molecules that support tissue repair and regeneration.

When injected into the skin, they help stimulate collagen production, improve hydration, and strengthen the skin over time.

This makes them particularly suitable for thin, fragile areas such as under the eyes.

How do polynucleotides work under the eyes?

Once injected, polynucleotides stimulate fibroblasts, the cells responsible for producing collagen and maintaining skin structure.

They also improve hydration within the skin, helping it appear smoother and more resilient. Over time, this leads to a brighter, more refreshed under-eye appearance.

Benefits of polynucleotides under eyes

Polynucleotides focus on improving overall skin quality rather than changing facial structure.

They can help to improve:

  • Fine lines and crepey skin
  • Thin under-eye skin
  • Dark circles linked to skin quality
  • Overall texture and hydration

Results appear natural and build gradually over time.

What results can you expect?

Most patients notice gradual improvements after a course of treatments.

This may include:

  • Smoother, more even skin
  • Improved hydration
  • A brighter, less tired appearance

Treatments are usually performed in a series, with results continuing to develop over several months.

What does treatment involve?

Polynucleotide treatment involves small injections into the under-eye area.

Practitioners may use either fine needles or a cannula depending on technique and suitability. The procedure typically takes around 20–30 minutes.

Mild swelling or small bumps can occur immediately after treatment but usually settle within 24 to 48 hours.

Will my eyes look swollen after treatment?

Some temporary swelling is normal and expected. This usually resolves quickly, and the skin often appears more hydrated soon after treatment.

Longer-term improvements develop gradually as the skin regenerates.

If this sounds like you

If your under-eye area looks tired, crepey, or thin, or if makeup tends to settle into fine lines, polynucleotides may be a suitable option.

They are ideal for those looking to improve skin quality without adding volume.

Polynucleotides improve the quality of the skin, while tear trough filler restores lost volume.

The best option depends on whether your concern is structural hollowing or skin quality. In some cases, both treatments may be used together.

At Vie Aesthetics, your treatment is always personalised

At Vie Aesthetics, we tailor every treatment to your individual needs.

As a doctor-led, CQC regulated clinic, we focus on achieving natural results through careful assessment and personalised treatment planning.

Refresh tired under eyes

Improve skin quality with regenerative treatments.

Polynucleotides under eyes: common questions

How long do results last?

Results can last several months, with maintenance treatments recommended.

Are they better than filler?

They treat different concerns. Polynucleotides improve skin quality, while filler restores volume.

Are they safe?

Yes, when performed by qualified professionals.

When will I see results?

Improvements develop gradually over a few weeks.

For those looking for a natural, medically guided treatment, it provides a strong option for long-term skin improvement.

Final thoughts

Polynucleotides offer a regenerative approach to under-eye rejuvenation, helping to improve the quality and resilience of the skin over time.

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Holborn,
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WC1X 8TX

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Rayleigh,
Essex,
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Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect
Polynucleotides Under Eyes UK: Benefits, Results and What to Expect