Crepey skin is one of the most common ageing concerns we hear about — and it’s not just limited to the face. The neck, arms, and décolleté often show early signs of thinning, loose, wrinkled skin, especially during and after menopause. Fortunately, regenerative treatments in 2025 offer you safer, smarter solutions that rebuild skin structure from within without the need for surgery.
Crepey skin appears thin, fragile, and wrinkled — like crêpe paper. It’s usually caused by:
Collagen and elastin loss due to ageing or hormonal changes
UV exposure breaking down skin fibres
Dryness or poor hydration
Rapid weight loss or muscle atrophy
Genetics and lifestyle factors (e.g., smoking, stress, poor diet)
Unlike sagging skin, crepey skin is more about surface texture and reduced firmness. You may notice it around the eyes, on the neck, inner arms, or chest.
Regenerative aesthetics uses biostimulating treatments that:
Trigger natural collagen and elastin production
Improve cellular turnover and hydration
Strengthen and repair the skin barrier
Rebuild skin structure from the inside out
This approach gives you gradual, natural improvements — ideal if you want to avoid artificial volume or dramatic changes.
Crepey skin can appear in multiple areas of the body, often in zones that are more delicate or exposed. Common treatment areas include:
Face: Especially under the eyes, where skin is thinnest and early signs of ageing are most visible
Neck: Prone to fine lines, sagging and loss of elasticity with age or weight fluctuations
Décolleté: The upper chest often develops lines from sun exposure and side-sleeping
Upper arms: A common concern in women post-40 due to thinning skin and collagen loss
Hands: Loss of plumpness and hydration creates a paper-like appearance
Stomach and inner thighs: Especially post-weight loss or pregnancy
Each area responds differently, so your practitioner will create a personalised plan based on skin condition, age, and desired outcome.
Polynucleotides are derived from purified salmon DNA and have a deep regenerative effect on skin tissues. They:
Improve elasticity and firmness
Repair damaged skin cells
Reduce inflammation and redness
Hydrate deeply and restore skin barrier
Best for: Eye area, neck, décolleté, and early signs of thinning or sensitive skin. Also ideal for menopausal or stressed skin.
Treatment plan: Usually 3–4 sessions spaced 2–4 weeks apart, then maintenance every few months.
Results: Smoother, stronger skin that improves over time.
Profhilo® is a stabilised hyaluronic acid injectable that spreads under the skin to deeply hydrate and stimulate collagen. It’s not a filler — it works by bio-remodelling skin tissue.
It:
Improves skin texture and elasticity
Targets crepey, lax skin without adding volume
Lifts and tightens in a very natural way
Best for: Neck, face, arms and décolleté — especially in clients 35+ seeing early signs of skin laxity.
Treatment plan: 2 sessions 4 weeks apart, then every 6 months.
Results: Firmer, bouncier skin with less crepiness and more luminosity.
PRP uses your own blood plasma, rich in growth factors, to stimulate collagen and improve skin quality.
It:
Encourages new collagen formation
Improves tone, firmness, and resilience
Supports healing and regeneration naturally
Best for: Thin, delicate areas like under-eyes, neck, and décolleté. Also excellent after sun damage or for mature skin.
Treatment plan: 3–4 sessions spaced a month apart.
Results: Gradual thickening and brightening of the skin.
Exosomes are tiny vesicles derived from stem cells that carry proteins, lipids, and genetic material to stimulate cellular repair.
They:
Promote new collagen and elastin production
Accelerate tissue healing and skin renewal
Calm inflammation and restore balance
Best for: Ageing, crepey, or dull skin that hasn’t responded to other treatments.
Treatment plan: Often used alongside microneedling or after other regenerative therapies for a powerful boost.
Results: Brighter, more youthful skin tone and texture, even in difficult-to-treat areas.
Key benefits: Stimulates skin repair, improves elasticity, deeply hydrates
Best for: Eyes, neck, chest
Downtime: Minimal — mild redness or swelling may occur
Key benefits: Boosts hydration, remodels ageing and lax skin
Best for: Face, neck, upper arms
Downtime: Minimal — some swelling or small lumps at injection sites for up to 24 hours
Key benefits: Uses your own plasma to trigger natural regeneration and collagen production
Best for: Under eyes, neck, chest
Downtime: 24–48 hours — possible redness, swelling, or bruising
Key benefits: Enhances cellular repair, reduces inflammation, improves skin quality
Best for: Face and body (can be applied after microneedling)
Downtime: None to minimal — depending on application method
Every case of crepey skin is different. At Vie Aesthetics, your journey begins with a detailed consultation to assess:
Your skin condition and medical history
Your goals, lifestyle and preferences
Areas of concern and severity
Whether combination therapy is more suitable
Many clients benefit from a combination of therapies for optimal results, for example:
Polynucleotides under the eyes with Profhilo® on the neck
Exosomes added to Dermapen 4™ microneedling to boost texture renewal on arms or décolleté
Our clinics are CQC-registered and doctor-led for your safety
We specialise in regenerative, non-surgical anti-ageing options
Every treatment is prescribed and administered by qualified medical professionals
We use only licensed and high-quality products
You’ll receive a bespoke treatment plan tailored to your needs
Our approach is holistic, transparent, and always led by evidence.
Whether you’re concerned about crepey skin on your neck, chest, arms or face, we’re here to help. Your first step is a consultation with one of our medical team or skin specialists, who will assess your needs and create a personalised plan.
2 Harley Street,
Marylebone,
London,
W1G 9PA, UK
